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Artigo Internacional sobre Otorrinolaringologia

Frequence of Appearance of Human Papillomavirus (HPV) in Oral Mucosa of Men with Anogenital HPV by a Molecular Technique
Author(s): Sandra Doria Xavier, Ivo Bussoloti Filho, Júlio Máximo de Carvalho, Valéria Maria de Souza Framil, Therezita Maria Peixoto Patury Galvão Castro.

Abstract: Human papillomavirus (HPV) is the aetiological factor of condyloma acuminatum which are the most common benign genital tumors in both sex. Currently, there is no doubt about the sexual transmission of this virus and it is recognized as the most frequent sexual transmitted disease nowadays. At the oral cavity, HPV can lead to benign lesions such as squamous cell papilloma, focal epithelial hyperplasia, condyloma acuminatum and verruca vulgaris. Based on the literature, the HPV prevalence at normal oral mucosa in patients with anogenital HPV infection is similar to the ones who have not anogenital HPV infection, what can suggest that this virus in the anogenital tract may not predispose others sites to be infected too.

Objective: The aim of this research is to determine oral HPV prevalence in male patients with anogenital HPV. This is a preliminary study, in which we studied 10 patients with anogenital HPV, confirmed by molecular biology. In all patients we performed an oral clinical investigation by scraping - in patients without oral lesions and biopsy - in patients with oral lesions.

Results: No patients had oral lesions nor HPV on their oral samples. Conclusion: So, from this pilot project, the virus at the anogenital tract seems not to predispose the oral cavity to be infected too. This conclusion is extremely important to patients with anogenital HPV infections since they are scared about the virus transmission to other sites of their bodies.

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